Patrick Mahomes threw for 360 yards and five touchdowns, lifting the Kansas City Chiefs to an impressive 44-21 road win over the Arizona Cardinals on Sunday in the opener for both teams.
The game was never in doubt after the opening minutes, with Mahomes picking apart the Cardinals' defense with his usual array of good decisions and deft passing touch. The quarterback was playing his first NFL game against Kliff Kingsbury, who coached Mahomes in college at Texas Tech and now leads the Cardinals.